Debbie (2 episodes)

Executive Producer (2 episodes)

Producer

Sue Ann

Linda Loman

Producer

Gladys Gibbes

Host (8 episodes)

Asmodius (voice)

Barb

Self (6 episodes)

Self (1 episode)

Officer Rhonda Tomasson (1 episode)

Self - Presenter (1 episode)

Detective Grinchauser (1 episode)

Host (3 episodes)

Executive Producer (3 episodes)

Self (2 episodes)

Self (1 episode)

Kimberly

Self (1 episode)

Narrator

Hattie Hayes

Self - Guest (2 episodes)

Emily Stanton

Self (1 episode)

Octavia Spencer (voice)

Grandma

Madam C. J. Walker (4 episodes)

Executive Producer (4 episodes)

Self (1 episode)

The Manticore (voice)

Dab-Dab (voice)

Poppy Scoville (28 episodes)

Executive Producer (28 episodes)

Harriet Wilson

Sue Ann

Executive Producer

Self (4 episodes)

Team Martha (1 episode)

Octavia Spencer (1 episode)

Executive Producer

Karen

Self - Panelist (1 episode)

Judy

Self (1 episode)

Kelly Banks

Executive Producer

Self (1 episode)

Zelda Fuller

Executive Producer

Self (3 episodes)

Roberta Taylor

Self - Host (1 episode)

Papa / Elouisa

Self (1 episode)

Dorothy Vaughan

Opal

Linda Workman

Mrs. Barrett

Johanna Reyes

Self (1 episode)

Mrs. Otterton (voice)

Miss Harris

Dr. Corman

Harriet Tubman (1 episode)

Johanna Reyes

Nurse Jackson (13 episodes)

Self (1 episode)

Rowena Jeffers

Aunt Honey

Self (1 episode)

Angel Angelique

Regina Tompkins (9 episodes)

Loray

Nurse Keller

Martha (voice)

Tanya

Wanda

Co-Executive Producer

Dr. Nance

Shonteeva (voice) (1 episode)

Octavia Spencer (1 episode)

LeSonia Robinson

Jenny

Madge Wiggins

Minny Jackson

Detention Teacher

Alison

Rhonda (segment "Auto Motives")

Madame Nora

Rhonda Dooley

Rochelle

Nurse Daniels

Arvina Watkins (5 episodes)

Bank Co-Worker

Troubled Woman

Professor Janack (1 episode)

Mrs. Hambrick

Kate the Home Health Care Nurse

Mary

Octavia (1 episode)

Nurse

Sherry (1 episode)

Dr. Evilini (2 episodes)

(1 episode)

(1 episode)

(10 episodes)

Streetwalker

Constance Grady (4 episodes)

Rapid Air Clerk (1 episode)

Landlady

Ayisha Lebaron

Jurist (1 episode)

Child Welfare Rep (1 episode)

Big Customer

Middle-Aged Woman

Woman

Mrs. Battle

Flight Attendant (6 episodes)

Stylist

Janine

Opal

Laqueta Mills

Neighbor in Alley

Security Guard

Unemployment Clerk

Sheryl Washington (1 episode)

Waitress

Check-In Girl

Ms. Alice Hays (2 episodes)

Gloria (1 episode)

Nurse B

Ruby Rydell (22 episodes)

Nurse #2

Hildy

(1 episode)

Black Belly

Elegant Guest (as Octavia L. Spencer)

Cashier (1 episode)

Ticket Woman (1 episode)

Waitress

Agnes Large

Twila

Nurse (1 episode)

Rhonda

Baby Nurse

Elegant guest (1 episode)

Hildy (1 episode)

Waitress (1 episode)

Nurse (1 episode)

Woman in Elevator

Nurse (1 episode)

(1 episode)

Shawna

Bus Driver (1 episode)

Cynthia

Evelyn

Duty Nurse (1 episode)

Maria Jones (1 episode)

Gloria (1 episode)

Wanda

Nativity Watson

Cheerleader

Roark's Nurse