The Starkeeper / Dr. Selden
John Everett Hughes
Dr. J. L. Pruitt
John Canfield (1 episode)
Governor Callahan (1 episode)
Mr. Caldwell (1 episode)
Dr. Charles Crandall
Eli Harcourt (1 episode)
Anthony Ghio
Judge Murdock
Mackenzie Savage
Charles McKendrick
Dr. Warren Kingsley, Sr
Aesop (voice) (815 episodes)
Murphy
Cicero P. Sweeney (1 episode)
Ben Franklin (voice)
Caro "Pop" Miller
Claude Mercadet
Toby Helper
Ben Dickason
Michael J. 'Mike' O'Connor
Richard Pennington Roeder
Dale Williams, Sr.
Jim Montgomery
Freddie Linley
Cherokee Jim
Dr. J.H. 'Doc' Fredericks
Stanley Slade
Sam Whitaker
Mr. Otis Skinner
Pa Dugan
Heinrich Block
Dr. Edgar Mason (as Charlie Ruggles)
Jim Pendergast
Chuckawalla Bill Redfield
Milo Everett
Harvey Wilson
Philo Swift
Milburn
Dick Piper
Buzz Nelson
Nicksie North
Nicki Popoff
Homer C. Fitch
Henry 'Pop' Hardy
Sweeney J. Patterson
Homer C. Fitch
Adam Tripp
Robinson
Sam Terwilliger
Himself
Horace Applegate
Tod Swain
J. Elliott Dinwiddy
Orville Shanks
Homer Bigelow
Charles Ruggles - Actor - Cameo Appearance (uncredited)
Sunbather (uncredited)
Chester R. Beatty
Himself (Uncredited)
Rev. Dr. Moon
Wilbur Sealingsworth
Edgar Holden
Henry Wilton
Egbert Floud
Aaron Kirkland
Asaph 'Ace' Holliday
Godfrey D. Scott
Warren Blodgett
J. Pinkham Whinney (as Charlie Ruggles)
March Hare
Vergil Crock
Oswald Groggs
Wilbur Todd
Pete Wells
Blackie Witherspoon
Peter Yates
Lieutenant Barton
Henry Peabody
Bimpfl
The Major
Philo Strawn (as Charlie Ruggles)
Johnny Moran
Viscount Gilbert de Varèze
Charles Ruggles (uncredited)
Bunny West
Adolph
Goliath Whitney (as Charlie Ruggles)
Clyde Saunders
Jerry Wells
Charlie Floyd
Monty Dunn
Fancourt Babberley
Bertie Bird
T. Boggs Johns
Shorty Ross
Willie Bindbugel
Charlie Tayler
Charlie Haven
Gaspard McMahon (an insurance clerk)
The Button Molder
Lawrence Evans